Skin ageing is a natural process, but changes in hydration, elasticity, and texture can become more noticeable over time. Fine lines, wrinkles, and dullness may appear as the skin’s natural renewal cycle slows down.
Developed in South Korea, the PN / PDRN Skin Healer offers a natural approach to hydrate skin and and rejuvenate skin cells from deep within, ultimately improving elasticity and repairing dry, damaged skin. It uses the active ingredient, polynucleotides (PN), a biological molecule known for its potential role in tissue regeneration and skin health. It naturally rejuvenates the skin cells by stimulating growth factors to accelerate the skin’s natural healing process to reverse skin damage, and increase collagen production. Over time, skin may appear smoother with smaller pore size, more supple, and revitalised, though individual results can vary.
A PN / PDRN Skin Healer is an injectable treatment that contains polynucleotides (PN), which are long chains of DNA fragments derived from salmon. These molecules have been studied for their potential role in supporting skin repair and rejuvenation. In aesthetic treatments, PN / PDRN is used to help improve hydration, elasticity, and overall skin texture.
The active ingredient is extracted from salmon DNA and processed for medical use under controlled conditions. It is delivered into the skin through a series of microinjections, allowing it to work beneath the surface to assist in the skin’s natural renewal processes.
The effectiveness of PN can be traced back to salmon DNA, a discovery supported by scientific studies on salmon DNA in skin applications (ScienceDirect). Research indicates that applying salmon DNA to human skin may improve elasticity, texture, and hyaluronic acid production, contributing to hydration. While results vary between individuals, such findings provide insight into the possible biological mechanisms behind PN / PDRN-based treatments.
The treatment works by depositing the active ingredients, polynucleotides (PN), into the mid to deep dermis of the skin through a series of precise microinjections. This is the layer just beneath the epidermis (outer skin), where collagen fibres, elastin, hyaluronic acid, and tiny blood vessels are found. These structures are essential for the skin’s strength, hydration, and repair.
By placing polynucleotides directly in the dermis:
Skin structure overview:
This targeted approach allows the treatment to work beneath the surface, where it can interact with the structures that support skin health. Skin booster injections can only be performed by trained medical professionals using sterile techniques aligned with medical standards.
A PN / PDRN Skin Healer may be considered by adults looking to hydrate, refresh, and strengthen their skin from within. This treatment is often chosen by:
As with any injectable procedure, this treatment is not suitable for everyone. People who are pregnant or breastfeeding, those with active skin infections, or individuals with allergies to the ingredients should avoid PDRN injections. A medical consultation at Halley Medical Aesthetics is required to determine suitability and tailor the treatment to each patient’s needs.
The use of polynucleotides (PN) derived from salmon DNA in this treatment provides multiple benefits that go beyond hydration alone. By supporting skin repair and collagen stimulation, a PN / PDRN Skin Healer treatment may help with:
Many patients describe a gradual, natural-looking improvement as the PN / PDRN skin healer continues to work beneath the skin surface, supporting repair and renewal.
The PN / PDRN Skin Healer is versatile and can be applied to various areas of the face and selected areas of the body, where it supports the skin’s natural repair and regeneration processes. By promoting healthier skin renewal and supporting collagen production, it helps improve skin resilience, elasticity, texture and overall skin quality, making it suitable for skin that appears weakened, damaged or affected by ageing.
The neck area is often the first to shows signs of ageing, such as fine lines, crepey skin, and sagging. The PN / PDRN Skin Healer treatment supports skin renewal and rejuvenation, providing a smoother and more youthful-looking neckline.
Hands can reveal our age faster than other body parts. The PN / PDRN Skin Healer rejuvenates ageing skin on the hands, reduces wrinkles, and restores youthful elasticity, resulting in a softer and more supple appearance.
The decolletage, often exposed to the elements, is particularly prone to sun damage, fine lines, and wrinkles. The PN / PDRN Skin Healer treatment works to revitalise this delicate area. It promotes skin healing and renewal to, smoothen uneven texture and reduce the visible signs of ageing. By restoring a radiant and youthful glow, it helps you feel more confident when wearing low-cut tops or dresses, letting you embrace your style with confidence.
The primary function of PN / PDRN Skin Healer is to support the skin’s natural repair and regeneration processes. By encouraging collagen production and reinforcing the skin’s structural support, the PN / PDRN Skin Healer helps our skin recover from age-related changes and environmental stress. It contains polynucleotides (PN) which are purified DNA fragments to help create a favourable environment for fibroblast activity, collagen production and tissue repair. This improves skin quality, elasticity, hydration and resilience over time.
In contrast, hydration-focused skin boosters, such as hyaluronic acid (HA) skin boosters and PN / PDRN skin boosters with HA, are primarily used to replenish moisture, improve skin hydration, and soften the appearance of fine lines. However, PN / PDRN Skin Healer takes a different approach, using PN to support the skin’s natural repair and regenerative processes.
PN / PDRN Skin Healer takes up to six weeks to see improvement. The treatment is best done three to four times at a two to four weekly intervals and repeated every three to six months for maintenance of healthy skin.
PN / PDRN Skin Healer takes up to six weeks to see improvement. The treatment is best done three to four times at a two to four weekly intervals and repeated every three to six months for maintenance of healthy skin.
Minimal post treatment care is needed. Tiny bumps may remain over the injection site for up to 12 hours. Needle marks, mild redness and bruises can occur but generally resolve rapidly and can be concealed with makeup.
Between your regularly scheduled PN / PDRN Skin Healer treatments, keep your skin healthy with the PDRN Skin Healing Treatment Facial designed to revitalise, repair, and lift tired and dehydrated skin. It combines polydeoxyribonucleotide (PDRN) which are shorter DNA fragments that are generally associated with tissue repair and regeneration with hyaluronic acid (HA) for moisturising the skin, and amino acids for firming the skin.
Read more: Treatment facials
To ensure optimal results and a smooth recovery following a PDRN Skin Healer treatment, it’s essential to avoid the following:
The use of these treatments/products is dependent on the clinical assessment and judgement of a medical professional. Please consult a medical doctor for an informed discussion on the use of this treatment/product.
