PN/ PDRN HA Skin Booster is an injectable skin booster treatment designed to revitalise, hydrate, and restore your skin from within. The scientifically developed formula combines Polynucleotides (PN), which are longer and purer DNA fragments (over 1,500 kDa) derived from salmon, with Hyaluronic Acid (HA) to help repair, regenerate, and deeply hydrate your skin for a healthier, more radiant, and youthful complexion.
Although PN is the main ingredient of this skin booster, Polydeoxyribonucleotide (PDRN) is often mentioned when the topic of skin booster is mentioned. PDRN is smaller in molecular size (50–1,500 kDa) and is used in tissue repair and skin healing treatments. Since they are often used interchangeably, the term “PN / PDRN” will be used when referring to this treatment.
Derived from salmon DNA fragments known for its regenerative properties, PN is used for anti-ageing and skin strengthening. It works synergistically with HA in this skin booster to improve overall skin texture, elasticity, and hydration.
Unlike dermal fillers that are designed to add volume or reshape facial contours, this treatment focuses on improving overall skin quality.
This treatment makes it one of the options available at aesthetic clinics in Singapore for individuals seeking a skin rejuvenation treatment that supports hydration and promotes skin health without adding volume.
PN / PDRN HA Skin Booster is an injectable skin rejuvenation treatment that combines two powerhouse ingredients:
The synergistic blend of PN and HA allows this skin booster to not only deliver hydration to the skin but also stimulate repair at the cellular level, supporting the skin’s structural integrity and radiance. This may be considered by individuals concerned about dullness, dehydration, fine lines, or weakened skin quality.
Those experiencing dryness or lacklustre skin due to environmental stress, ageing, or lifestyle habits may benefit from the hydration properties of HA, which helps improve overall skin radiance.
If you’ve noticed a rough or uneven texture, this treatment may help support natural repair processes for smoother, more supple skin.
Fine lines, especially around the eyes and mouth, may appear due to dehydration and decreased collagen. PN / PDRN aims to support skin structure and firmness over time.
This treatment is suited for individuals who prefer natural-looking results and are not looking to add volume to their face.
PN / PDRN has been studied for its role in skin recovery, making it suitable as a post-procedure or post-environmental stress skin support option when advised by a clinician.
HA retains moisture in the skin, which may help relieve dryness and restore a healthier glow.
PN / PDRN work at the cellular level to support tissue repair and may reduce the appearance of roughness or unevenness over time.
By encouraging collagen activity, this skin booster may help firm up lax areas and reduce the appearance of sagging.
Hydrated and healthier skin can appear plumper, which may help minimise the look of fine lines, especially on the forehead and around the eyes.
With improved hydration, elasticity, and cell renewal, the skin becomes healthier, looks brighter, more refreshed, and more youthful.
Individual results may vary depending on skin type, lifestyle, and treatment plan.
Both PN and its subset PDRN have been studied for their ability to support skin recovery and cellular activity. This skin booster is formulated with evidence-backed components that work in tandem to refresh tired, dehydrated skin.
At Halley Medical Aesthetics, the treatment plan is tailored to your skin needs and preferences after a comprehensive consultation.
Whether you're hoping to delay early signs of skin ageing or improve the appearance of dullness, fine lines, and dryness, this treatment supports both preventive care and targeted rejuvenation.
Yes, it can be safely combined with other aesthetic treatments for optimal skin rejuvenation results. Pairing it with complementary treatments can help target multiple concerns for a holistic approach to treatment. Whether treatments can be performed on the same day will depend on your individual skin condition and treatment plan. It is best to consult your doctor, who will advise on the most appropriate approach for your needs.
Some common treatment combinations in Singapore include:
Laser treatments such as Pico laser rejuvenation address pigmentation and dull skin tone. PN / PDRN supports our body’s skin repair needs after a laser treatment while HA enhances recovery by restoring our skin’s moisture level and reinforcing our skin’s natural protective barrier.
Combining with botulinum neuromodulators can address both dynamic wrinkles and skin texture concerns in one treatment plan.
Dermal fillers complement PN / PDRN Skin Booster for those seeking both hydration and volume restoration for a more amplified skin rejuvenation.
Treatments such as no downtime chemical peels and medical-grade facials clears pores, and prepares the skin so that it can fully absorb the skin healing, rejuvenating, and hydrating properties of the PN / PDRN Skin Booster.
Yes, it is safe when carried out by trained medical professionals. The key ingredients—PN and HA—are formulated and processed under stringent medical-grade safety standards. At Halley Medical Aesthetics, all procedures are performed in a licensed clinical environment following regulatory protocols to maintain patient safety and hygiene.
Tiny bumps may appear at the injection site for up to 12 hours. Patients may also see needle marks, mild redness, and bruises, but these generally resolve quickly by themselves and can be concealed with makeup.
Patients may notice early improvements in skin hydration and skin texture five days after the first session, although results are optimal after three sessions. With continued treatments, you will notice more visible changes, such as improved skin elasticity, smoother texture, and reduced fine lines
For optimal results, doctors usually recommend three sessions of treatment, each spaced one month apart. Collagen remodelling occurs around three to six months after the whole course of treatment.
While HA Skin Boosters focus primarily on skin hydration, PN / PDRN HA Skin Booster also stimulates tissue repair and skin regeneration due to the addition of PN, offering a more comprehensive skin rejuvenation effect.
To ensure optimal results and minimise side effects, please follow these post-treatment care guidelines:
Yes, PN / PDRN HA skin boosters can safely be combined with doctor treatments such as lasers, botulinum toxin, or fillers. Your doctor will advise on the ideal sequence or same-day combined treatment based on your skin condition and prescribed treatments.
If you are looking for a skin booster treatment in Singapore that goes beyond hydration to repair and regenerate your skin, PN/PDRN HA skin booster may be what you need. Book a consultation with us to see if this treatment is right for your skin goals.
