PN / PDRN Skin Boosters are injectable treatments formulated with polynucleotides (PN) derived from purified salmon DNA fragments. These treatments can help stimulate collagen production and support the skin’s natural healing processes, improving elasticity and overall skin quality.
Unlike Hyaluronic Acid (HA) Skin Boosters, which primarily improve skin hydration to make our skin appear plumper and more supple, PN / PDRN formulations work by helping to repair damaged or ageing skin. At Halley Medical Aesthetics, we offer four PN / PDRN Skin Booster options to address different aspects of skin quality and texture.
Common treatment areas include:
Our doctors will recommend a suitable formulation and craft a personalised treatment plan based on your skin condition and treatment goals.
PN / PDRN Skin Boosters contain purified DNA fragments commonly derived from salmon. These fragments activate adenosine A2A receptors, which are naturally occurring receptors that help regulate how the skin responds to injury and inflammation.
When activated, these receptors encourage fibroblasts (the cells responsible for producing collagen), support the formation of new blood vessels, and help reduce inflammation. Together, these processes support skin repair, collagen production, and gradually improve elasticity and overall skin quality.
Depending on your skin condition and treatment goals, our doctors may recommend PN / PDRN Skin Boosters if you have:
Your doctor will assess your skin condition, concerns, medical history, and treatment goals before recommending a suitable PN / PDRN Skin Booster. They will also determine the treatment area, and session frequency.
We will first apply numbing cream and leave it on for 15 to 20 minutes before treatment to improve comfort.
Your doctor will then deliver the skin booster through a series of small injections. This process will usually take around 30 minutes.
You may notice small bumps, needle marks, mild redness, swelling, or bruising after treatment. These effects usually settle within several hours to a few days, although the recovery time can vary depending on the treatment area and injection method.
Your doctor will provide aftercare instructions based on the treatment performed. In general, you should avoid makeup immediately after treatment, as well as alcohol, vigorous exercise, saunas, steam rooms, and excessive heat for the first 24 hours. This prevents infection, minimises bruising, and supports recovery.
Results usually develop gradually as the skin responds to the treatment. Depending on the formulation used, you may begin to notice improvements within one to six weeks, with further changes developing across the recommended treatment course.
The duration varies according to the product used, your skin condition, and the number of sessions completed. Most PN / PDRN Skin Boosters require an initial course of three monthly treatments, followed by maintenance around every six months.
The cost depends on the formulation selected and the number of sessions recommended. Please refer to our price list for the latest skin booster prices.
Yes, they may be suitable for people with sensitive skin. However, your doctor will first assess your skin condition and any active inflammation or irritation to determine whether treatment is appropriate.
You will feel brief pinpricks or mild pressure during the injections. We will apply numbing cream for around 15 to 20 minutes before the treatment to help improve comfort.
Yes. Depending on your skin concerns, doctors may use PN/PDRN skin boosters on the neck and hands to help improve skin quality, elasticity, and the appearance of ageing skin.
It depends. If you have active acne or an active skin infection in the treatment area, your doctor may recommend treating the underlying condition first. Once the skin is suitable for treatment, they will advise whether a repair and recovery skin booster is appropriate.
When choosing an aesthetic clinic for PN / PDRN Skin Boosters, look beyond the number of products offered and consider whether the doctor understands the differences between the available formulations and their intended uses. A thorough assessment should consider your skin condition, concerns, and treatment goals before determining which formulation and injection approach are appropriate.
The use of these treatments/products is dependent on the clinical assessment and judgement of a medical professional. Please consult a medical doctor for an informed discussion on the use of this treatment/product.
